{"id": "card_works_medicine", "kind": "verified", "title": "The body's numbers: mean pressure and a safe dose", "body": "Mean arterial pressure — what actually perfuses the organs — is DBP + (SBP−DBP)/3, about 93 mmHg at 120/80. And a 10 mg/kg drug in a 70 kg adult is a 700 mg dose. The bedside arithmetic that must not be wrong.  Worked & sealed by the engine — MAP = 80 + (120−80)/3 ≈ 93.3 mmHg · dose = 10 mg/kg · 70 kg = 700 mg.  [HOLDS; open the seal to re-check.]", "source": {"label": "The Works — worked & sealed", "url": "https://narrowhighway.com/s/124c8a5e91f820c55306fa564638e32400adc9466560b7ed59ca907278cb91aa", "domain": "medicine", "authority_tier": "verified"}, "shelf": "the-works", "box": "earth_life", "bands": ["the-works", "earth_life", "medicine", "clinical", "medicine"], "connections": [{"to_card_id": "card_spine_the-works", "relationship": "member_of", "evidence": "a member of the the-works shelf in the keeping"}, {"to_card_id": "card_k_floor_of_discovery", "relationship": "paves", "evidence": "A worked, engine-sealed demonstration — a paving-stone of the floor of reality."}, {"to_card_id": "card_v_e6283405b201", "relationship": "demonstrates", "evidence": "A worked demonstration in the same field (medicine)."}, {"to_card_id": "card_works_nested_control", "relationship": "adjacent", "evidence": "Neighbouring worked demonstrations in the same part of the volume."}, {"to_card_id": "card_works_wave_speed", "relationship": "adjacent", "evidence": "Neighbouring worked demonstrations in the same part of the volume."}], "author": "engine", "created_at": 0.0, "updated_at": 0.0, "visibility": "public", "lifecycle_stage": "public", "volatility": "permanent", "surface": "secular", "generated": false, "subject": "Clinical medicine", "extra": {"seal_hash": "124c8a5e91f820c55306fa564638e32400adc9466560b7ed59ca907278cb91aa", "cite_url": "https://narrowhighway.com/s/124c8a5e91f820c55306fa564638e32400adc9466560b7ed59ca907278cb91aa", "demonstration_id": "works_medicine", "verdict": "HOLDS"}, "presentation": {"glyph": "•", "kind_label": "earth life", "by": "The Works — worked & sealed", "authority": "verified", "posted": "", "standing": "", "link": {"url": "https://narrowhighway.com/s/124c8a5e91f820c55306fa564638e32400adc9466560b7ed59ca907278cb91aa", "host": "narrowhighway.com", "provider": "", "titled": "The body's numbers: mean pressure and a safe dose", "waybill_line": "", "reach": "", "embed": ""}}, "neighbors": [{"id": "card_spine_the-works", "title": "The Works — sealed, worked demonstrations", "relationship": "on the shelf of", "why": "a member of the the-works shelf in the keeping", "href": "/card/card_spine_the-works", "resolved": true}, {"id": "card_k_floor_of_discovery", "title": "The Floor of Discovery — one floor, and by its design the fear of God", "relationship": "paves", "why": "A worked, engine-sealed demonstration — a paving-stone of the floor of reality.", "href": "/card/card_k_floor_of_discovery", "resolved": true}, {"id": "card_v_e6283405b201", "title": "MAP = 80 + (120−80)/3 ≈ 93.3 mmHg · dose = 10 mg/kg · 70 kg = 700 mg", "relationship": "demonstrates", "why": "A worked demonstration in the same field (medicine).", "href": "/card/card_v_e6283405b201", "resolved": true}, {"id": "card_works_nested_control", "title": "The nested control-systems rule: meet a failure at its own layer", "relationship": "adjacent", "why": "Neighbouring worked demonstrations in the same part of the volume.", "href": "/card/card_works_nested_control", "resolved": true}, {"id": "card_works_wave_speed", "title": "How fast a 100-metre ocean swell travels", "relationship": "adjacent", "why": "Neighbouring worked demonstrations in the same part of the volume.", "href": "/card/card_works_wave_speed", "resolved": true}]}