{"id": "card_ncs_l2_lc_ne_adaptive_gain", "kind": "reference", "title": "LC-NE Adaptive Gain", "body": "Level 2 of the Nested Control-Systems stack. Precision & arousal gating: tonic locus-coeruleus / norepinephrine sets baseline arousal, phasic bursts boost task precision; high-tonic/low-phasic = overload and poor transitions. These layers do not compete; they nest — each operates at a different level of one causal system, which is why treating them as rivals was a decades-long error. Source: Aston-Jones & Cohen (2005), Annu. Rev. Neurosci. 28:403.", "source": {"label": "Aston-Jones & Cohen (2005), Annu. Rev. Neurosci. 28:403.", "url": "", "domain": "biology", "authority_tier": "reference"}, "shelf": "regulation", "box": "nested control systems", "bands": ["nested control systems", "regulation", "control theory", "level 2", "LC-NE", "locus coeruleus", "norepinephrine", "arousal", "adaptive gain", "RAS"], "connections": [{"to_card_id": "card_k_ncs_validation", "relationship": "member_of", "evidence": "a spine theory (a level of the one nested control-systems stack)"}, {"to_card_id": "card_ncs_l1_predictive_processing", "relationship": "modulates", "evidence": "the next level down in the control stack (higher command → lower effector)"}, {"to_card_id": "card_ncs_l3_neurovisceral_integration", "relationship": "modulates", "evidence": "the next level down in the control stack (higher command → lower effector)"}], "author": "engine", "created_at": 0.0, "updated_at": 0.0, "visibility": "public", "lifecycle_stage": "public", "volatility": "permanent", "surface": "secular", "generated": false, "subject": "LC-NE Adaptive Gain", "presentation": {"glyph": "•", "kind_label": "nested control systems", "by": "Aston-Jones & Cohen (2005), Annu. Rev. Neurosci. 28:403.", "authority": "reference", "posted": "", "standing": ""}, "neighbors": [{"id": "card_k_ncs_validation", "title": "Nested Control Systems — a pre-registered falsification program (NHANES)", "relationship": "on the shelf of", "why": "a spine theory (a level of the one nested control-systems stack)", "href": "/card/card_k_ncs_validation", "resolved": true}, {"id": "card_ncs_l1_predictive_processing", "title": "Predictive Processing / Active Inference", "relationship": "modulates", "why": "the next level down in the control stack (higher command → lower effector)", "href": "/card/card_ncs_l1_predictive_processing", "resolved": true}, {"id": "card_ncs_l3_neurovisceral_integration", "title": "Neurovisceral Integration / Central Autonomic Network", "relationship": "modulates", "why": "the next level down in the control stack (higher command → lower effector)", "href": "/card/card_ncs_l3_neurovisceral_integration", "resolved": true}]}