The one test that would kill it — layer-specific versus matched-generic, within one person

A real theory FORBIDS something. The red-team's central fix gives this framework its forbidden prediction — a concrete result stated in advance that, if observed, ends it: THE TEST. Take a person whose failing layer has been identified by a PRE-REGISTERED assignment protocol (with a measured inter-rater reliability number — no protocol, no test). Run a within-person crossover: a LAYER-SPECIFIC intervention versus a MATCHED GENERIC one (equal effort, dose, duration, expectation). Measure the target layer's marker as a recovery slope. THE FORBIDDEN OUTCOME. The framework predicts specific > generic, replicated. If matched-generic moves the marker as much as — or more than — layer-specific, across pre-set replications, the layer model is DEAD: it added vocabulary, not leverage. That outcome is possible and observable — sealed satisfiable (https://narrowhighway.com/s/cdacdaa79a2ec7dcf23ba1f2c8171040af7fbf97dae40dbe5e33ce21418a3544) — which is exactly what makes this a theory and not a flexible lens. The falsification timeline names the checkpoints: baseline variability (weeks 1-4; no within-person variance ⇒ measurement problem), perturbation co-variation (weeks 5-12; markers don't track dysregulation ⇒ wrong ladder), intervention (months 4-6; behavior changes but markers don't ⇒ epiphenomenal markers), causal disambiguation (months 7-12; change the marker, does behavior follow?). Each checkpoint can END the framework. That is the point. In its author's words: "if the structure is sound it will generate fruit; if not, no protection would matter." SAFETY BOUNDARY — this is a research framework, NOT medical advice, NOT a diagnosis, NOT a treatment plan. It is adjunctive to, never a replacement for, a licensed physician. STOP and seek urgent care for red flags: chest pain, sudden neurological deficit, fainting, severe or rapidly worsening symptoms. The engine seals the LOGIC of this framework; it does NOT and CANNOT seal that any mechanism here is medically true — that awaits the trials named below.