NarrowHighway

The genome as information — and the algebra of a population

Two bits per base, sealed: log(4)/log(2) = 2 — so the ~3.2 billion base pairs of the human genome hold ~6.4 billion bits, about 800 MB, a large app's worth of code in every cell (https://narrowhighway.com/s/632994d71f8e8f5559fcdb14b7802295952064adf5fb410613686c3526381bdd). 23 chromosome pairs make 46 (sealed). And a whole population obeys simple algebra: Hardy-Weinberg says (p+q)^2 = p^2 + 2pq + q^2, so for a recessive allele at frequency 0.3, carriers run 2·0.7·0.3 = 0.42 of the population — sealed (https://narrowhighway.com/s/ff5890c84d43e6059e004eae6b6f5d2ee7c0c0e44659963dd8ff61fc34ca0ca2 ). The information view is exact; what the information MEANS (which sequence folds to which working protein) is empirical biology, and protein folding from sequence is itself an open hard problem the map would mark INCOMPLETE.

source
Concordance assay — 2026-07-09 · genetics ↗
card id
card_n_49d1ebe5ba6a

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